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Transportin 3 Promotes a Nuclear Maturation Step Required for Efficient HIV-1 Integration
The HIV/AIDS pandemic is a major global health threat and understanding the detailed molecular mechanisms of HIV replication is critical for the development of novel therapeutics. To replicate, HIV-1 must access the nucleus of infected cells and integrate into host chromosomes, however little is kno...
Autores principales: | Zhou, Lihong, Sokolskaja, Elena, Jolly, Clare, James, William, Cowley, Sally A., Fassati, Ariberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161976/ https://www.ncbi.nlm.nih.gov/pubmed/21901095 http://dx.doi.org/10.1371/journal.ppat.1002194 |
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