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Disruption of PML Nuclear Bodies Is Mediated by ORF61 SUMO-Interacting Motifs and Required for Varicella-Zoster Virus Pathogenesis in Skin

Promyelocytic leukemia protein (PML) has antiviral functions and many viruses encode gene products that disrupt PML nuclear bodies (PML NBs). However, evidence of the relevance of PML NB modification for viral pathogenesis is limited and little is known about viral gene functions required for PML NB...

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Detalles Bibliográficos
Autores principales: Wang, Li, Oliver, Stefan L., Sommer, Marvin, Rajamani, Jaya, Reichelt, Mike, Arvin, Ann M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161977/
https://www.ncbi.nlm.nih.gov/pubmed/21901090
http://dx.doi.org/10.1371/journal.ppat.1002157