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Aquatic Birnavirus-Induced ER Stress-Mediated Death Signaling Contribute to Downregulation of Bcl-2 Family Proteins in Salmon Embryo Cells

Aquatic birnavirus induces mitochondria-mediated cell death, but whether connects to endoplasmic reticulum (ER) stress is still unknown. In this present, we characterized that IPNV infection triggers ER stress-mediated cell death via PKR/eIF2α phosphorylation signaling for regulating the Bcl-2 famil...

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Detalles Bibliográficos
Autores principales: Huang, Hui Ling, Wu, Jen Leih, Chen, Mark Hung Chih, Hong, Jiann Ruey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161983/
https://www.ncbi.nlm.nih.gov/pubmed/21901118
http://dx.doi.org/10.1371/journal.pone.0022935