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Beta-HPV 5 and 8 E6 Promote p300 Degradation by Blocking AKT/p300 Association

The E6 oncoprotein from high-risk genus alpha human papillomaviruses (α-HPVs), such as HPV 16, has been well characterized with respect to the host-cell proteins it interacts with and corresponding signaling pathways that are disrupted due to these interactions. Less is known regarding the interacti...

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Detalles Bibliográficos
Autores principales: Howie, Heather L., Koop, Jennifer I., Weese, Joleen, Robinson, Kristin, Wipf, Greg, Kim, Leslie, Galloway, Denise A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161984/
https://www.ncbi.nlm.nih.gov/pubmed/21901101
http://dx.doi.org/10.1371/journal.ppat.1002211