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Absence of Cross-Presenting Cells in the Salivary Gland and Viral Immune Evasion Confine Cytomegalovirus Immune Control to Effector CD4 T Cells

Horizontal transmission of cytomegaloviruses (CMV) occurs via prolonged excretion from mucosal surfaces. We used murine CMV (MCMV) infection to investigate the mechanisms of immune control in secretory organs. CD4 T cells were crucial to cease MCMV replication in the salivary gland (SG) via direct s...

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Detalles Bibliográficos
Autores principales: Walton, Senta M., Mandaric, Sanja, Torti, Nicole, Zimmermann, Albert, Hengel, Hartmut, Oxenius, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161985/
https://www.ncbi.nlm.nih.gov/pubmed/21901102
http://dx.doi.org/10.1371/journal.ppat.1002214