Direct Observation of Single Amyloid-β(1-40) Oligomers on Live Cells: Binding and Growth at Physiological Concentrations

Understanding how amyloid-β peptide interacts with living cells on a molecular level is critical to development of targeted treatments for Alzheimer's disease. Evidence that oligomeric Aβ interacts with neuronal cell membranes has been provided, but the mechanism by which membrane binding occur...

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Detalles Bibliográficos
Autores principales: Johnson, Robin D., Schauerte, Joseph A., Wisser, Kathleen C., Gafni, Ari, Steel, Duncan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162019/
https://www.ncbi.nlm.nih.gov/pubmed/21901146
http://dx.doi.org/10.1371/journal.pone.0023970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162019/
https://www.ncbi.nlm.nih.gov/pubmed/21901146
http://dx.doi.org/10.1371/journal.pone.0023970

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