Lowe Syndrome Protein OCRL1 Supports Maturation of Polarized Epithelial Cells

Mutations in the inositol polyphosphate 5-phosphatase OCRL1 cause Lowe Syndrome, leading to cataracts, mental retardation and renal failure. We noted that cell types affected in Lowe Syndrome are highly polarized, and therefore we studied OCRL1 in epithelial cells as they mature from isolated indivi...

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Detalles Bibliográficos
Autores principales: Grieve, Adam G., Daniels, Rachel D., Sanchez-Heras, Elena, Hayes, Matthew J., Moss, Stephen E., Matter, Karl, Lowe, Martin, Levine, Timothy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162020/
https://www.ncbi.nlm.nih.gov/pubmed/21901156
http://dx.doi.org/10.1371/journal.pone.0024044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162020/
https://www.ncbi.nlm.nih.gov/pubmed/21901156
http://dx.doi.org/10.1371/journal.pone.0024044

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