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Molecular Genetic Analysis of 103 Sporadic Colorectal Tumours in Czech Patients

The Czech Republic has one of the highest incidences of colorectal cancer (CRC) in Europe. To evaluate whether sporadic CRCs in Czech patients have specific mutational profiles we analysed somatic genetic changes in known CRC genes (APC, KRAS, TP53, CTNNB1, MUTYH and BRAF, loss of heterozygosity (LO...

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Detalles Bibliográficos
Autores principales: Vasovcak, Peter, Pavlikova, Kristyna, Sedlacek, Zdenek, Skapa, Petr, Kouda, Martin, Hoch, Jiri, Krepelova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162034/
https://www.ncbi.nlm.nih.gov/pubmed/21901162
http://dx.doi.org/10.1371/journal.pone.0024114