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Maternal Obesity during Gestation Impairs Fatty Acid Oxidation and Mitochondrial SIRT3 Expression in Rat Offspring at Weaning

In utero exposure to maternal obesity increases the offspring's risk of obesity in later life. We have also previously reported that offspring of obese rat dams develop hepatic steatosis, mild hyperinsulinemia, and a lipogenic gene signature in the liver at postnatal day (PND)21. In the current...

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Detalles Bibliográficos
Autores principales: Borengasser, Sarah J., Lau, Franchesca, Kang, Ping, Blackburn, Michael L., Ronis, Martin J. J., Badger, Thomas M., Shankar, Kartik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162035/
https://www.ncbi.nlm.nih.gov/pubmed/21901160
http://dx.doi.org/10.1371/journal.pone.0024068