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Maternal Obesity during Gestation Impairs Fatty Acid Oxidation and Mitochondrial SIRT3 Expression in Rat Offspring at Weaning
In utero exposure to maternal obesity increases the offspring's risk of obesity in later life. We have also previously reported that offspring of obese rat dams develop hepatic steatosis, mild hyperinsulinemia, and a lipogenic gene signature in the liver at postnatal day (PND)21. In the current...
Autores principales: | Borengasser, Sarah J., Lau, Franchesca, Kang, Ping, Blackburn, Michael L., Ronis, Martin J. J., Badger, Thomas M., Shankar, Kartik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162035/ https://www.ncbi.nlm.nih.gov/pubmed/21901160 http://dx.doi.org/10.1371/journal.pone.0024068 |
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