Interleukin-2 is Present in Human Blood Vessels and Released in Biologically Active Form by Heparanase

Interleukin-2 is a multifaceted cytokine with both immunostimulatory and immunosuppressive properties. Our laboratory recently demonstrated that the availability of IL-2 is regulated, in part, by association with perlecan, a heparan sulfate proteoglycan. Given the abundance of perlecan in blood vess...

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Detalles Bibliográficos
Autores principales: Miller, John D., Clabaugh, Suzanne E., Smith, Deandra R., Stevens, R. B., Wrenshall, Lucile E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162067/
https://www.ncbi.nlm.nih.gov/pubmed/21606942
http://dx.doi.org/10.1038/icb.2011.45

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162067/
https://www.ncbi.nlm.nih.gov/pubmed/21606942
http://dx.doi.org/10.1038/icb.2011.45

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