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Interleukin-2 is Present in Human Blood Vessels and Released in Biologically Active Form by Heparanase
Interleukin-2 is a multifaceted cytokine with both immunostimulatory and immunosuppressive properties. Our laboratory recently demonstrated that the availability of IL-2 is regulated, in part, by association with perlecan, a heparan sulfate proteoglycan. Given the abundance of perlecan in blood vess...
Autores principales: | Miller, John D., Clabaugh, Suzanne E., Smith, Deandra R., Stevens, R. B., Wrenshall, Lucile E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162067/ https://www.ncbi.nlm.nih.gov/pubmed/21606942 http://dx.doi.org/10.1038/icb.2011.45 |
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