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Epidermal Growth Factor Protects the Apical Junctional Complexes from Hydrogen peroxide in Bile Duct Epithelium

The tight junctions of bile duct epithelium form a barrier between the toxic bile and liver parenchyma. Disruption of tight junctions appears to play a crucial role in the pathogenesis of various liver diseases. In this study, we investigated the disruptive effect of hydrogen peroxide and the protec...

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Detalles Bibliográficos
Autores principales: Guntaka, Srikar R., Samak, Geetha, Seth, Ankur, LaRusso, Nicholas F., Rao, Radhakrishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162098/
https://www.ncbi.nlm.nih.gov/pubmed/21606925
http://dx.doi.org/10.1038/labinvest.2011.73