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The SKP1-Cul1-F-box and Leucine-rich Repeat Protein 4 (SCF-FbxL4) Ubiquitin Ligase Regulates Lysine Demethylase 4A (KDM4A)/Jumonji Domain-containing 2A (JMJD2A) Protein

Chromatin-modifying enzymes play a fundamental role in regulating chromatin structure so that DNA replication is spatially and temporally coordinated. For example, the lysine demethylase 4A/Jumonji domain-containing 2A (KDM4A/JMJD2A) is tightly regulated during the cell cycle. Overexpression of JMJD...

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Detalles Bibliográficos
Autores principales: Van Rechem, Capucine, Black, Joshua C., Abbas, Tarek, Allen, Andrew, Rinehart, Claire A., Yuan, Guo-Cheng, Dutta, Anindya, Whetstine, Johnathan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162406/
https://www.ncbi.nlm.nih.gov/pubmed/21757720
http://dx.doi.org/10.1074/jbc.M111.273508