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Post-production protein stability: trouble beyond the cell factory

Being protein function a conformation-dependent issue, avoiding aggregation during production is a major challenge in biotechnological processes, what is often successfully addressed by convenient upstream, midstream or downstream approaches. Even when obtained in soluble forms, proteins tend to agg...

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Detalles Bibliográficos
Autores principales: Vazquez, Esther, Corchero, José Luis, Villaverde, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162505/
https://www.ncbi.nlm.nih.gov/pubmed/21806813
http://dx.doi.org/10.1186/1475-2859-10-60