SERCA2a gene transfer improves electrocardiographic performance in aged mdx mice

BACKGROUND: Cardiomyocyte calcium overloading has been implicated in the pathogenesis of Duchenne muscular dystrophy (DMD) heart disease. The cardiac isoform of sarcoplasmic reticulum calcium ATPase (SERCA2a) plays a major role in removing cytosolic calcium during heart muscle relaxation. Here, we t...

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Detalles Bibliográficos
Autores principales: Shin, Jin-Hong, Bostick, Brian, Yue, Yongping, Hajjar, Roger, Duan, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162513/
https://www.ncbi.nlm.nih.gov/pubmed/21834967
http://dx.doi.org/10.1186/1479-5876-9-132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162513/
https://www.ncbi.nlm.nih.gov/pubmed/21834967
http://dx.doi.org/10.1186/1479-5876-9-132

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