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Inferring causal genomic alterations in breast cancer using gene expression data

BACKGROUND: One of the primary objectives in cancer research is to identify causal genomic alterations, such as somatic copy number variation (CNV) and somatic mutations, during tumor development. Many valuable studies lack genomic data to detect CNV; therefore, methods that are able to infer CNVs f...

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Detalles Bibliográficos
Autores principales: Tran, Linh M, Zhang, Bin, Zhang, Zhan, Zhang, Chunsheng, Xie, Tao, Lamb, John R, Dai, Hongyue, Schadt, Eric E, Zhu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162519/
https://www.ncbi.nlm.nih.gov/pubmed/21806811
http://dx.doi.org/10.1186/1752-0509-5-121