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Albiglutide, a Long Lasting Glucagon-Like Peptide-1 Analog, Protects the Rat Heart against Ischemia/Reperfusion Injury: Evidence for Improving Cardiac Metabolic Efficiency

BACKGROUND: The cardioprotective effects of glucagon-like peptide-1 (GLP-1) and analogs have been previously reported. We tested the hypothesis that albiglutide, a novel long half-life analog of GLP-1, may protect the heart against I/R injury by increasing carbohydrate utilization and improving card...

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Detalles Bibliográficos
Autores principales: Bao, Weike, Aravindhan, Karpagam, Alsaid, Hasan, Chendrimada, Thimmaiah, Szapacs, Matthew, Citerone, David R., Harpel, Mark R., Willette, Robert N., Lepore, John J., Jucker, Beat M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162574/
https://www.ncbi.nlm.nih.gov/pubmed/21887274
http://dx.doi.org/10.1371/journal.pone.0023570