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Regulation of the stem cell marker CD133 is independent of promoter hypermethylation in human epithelial differentiation and cancer

BACKGROUND: Epigenetic control is essential for maintenance of tissue hierarchy and correct differentiation. In cancer, this hierarchical structure is altered and epigenetic control deregulated, but the relationship between these two phenomena is still unclear. CD133 is a marker for adult stem cells...

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Detalles Bibliográficos
Autores principales: Pellacani, Davide, Packer, Richard J, Frame, Fiona M, Oldridge, Emma E, Berry, Paul A, Labarthe, Marie-Christine, Stower, Michael J, Simms, Matthew S, Collins, Anne T, Maitland, Norman J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162587/
https://www.ncbi.nlm.nih.gov/pubmed/21801380
http://dx.doi.org/10.1186/1476-4598-10-94