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Pathogenicity and Rapid Growth Kinetics of Feline Immunodeficiency Virus Are Linked to 3′ Elements

Chimeric viruses constructed between a highly pathogenic Feline Immunodeficiency Virus isolate (FIV-C36) and a less pathogenic but neurotropic strain (FIV-PPR) have been used to map viral genetic determinants of in vivo pathogenicity. Chimeric virus FIV-PCenv, which contains FIV-C36 genome from the...

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Detalles Bibliográficos
Autores principales: Thompson, Jesse, MacMillan, Martha, Boegler, Karen, Wood, Charles, Elder, John H., VandeWoude, Sue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162592/
https://www.ncbi.nlm.nih.gov/pubmed/21887365
http://dx.doi.org/10.1371/journal.pone.0024020