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Myosin IIB Activity and Phosphorylation Status Determines Dendritic Spine and Post-Synaptic Density Morphology

Dendritic spines in hippocampal neurons mature from a filopodia-like precursor into a mushroom-shape with an enlarged post-synaptic density (PSD) and serve as the primary post-synaptic location of the excitatory neurotransmission that underlies learning and memory. Using myosin II regulatory mutants...

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Detalles Bibliográficos
Autores principales: Hodges, Jennifer L., Newell-Litwa, Karen, Asmussen, Hannelore, Vicente-Manzanares, Miguel, Horwitz, Alan Rick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162601/
https://www.ncbi.nlm.nih.gov/pubmed/21887379
http://dx.doi.org/10.1371/journal.pone.0024149