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Myosin IIB Activity and Phosphorylation Status Determines Dendritic Spine and Post-Synaptic Density Morphology
Dendritic spines in hippocampal neurons mature from a filopodia-like precursor into a mushroom-shape with an enlarged post-synaptic density (PSD) and serve as the primary post-synaptic location of the excitatory neurotransmission that underlies learning and memory. Using myosin II regulatory mutants...
Autores principales: | Hodges, Jennifer L., Newell-Litwa, Karen, Asmussen, Hannelore, Vicente-Manzanares, Miguel, Horwitz, Alan Rick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162601/ https://www.ncbi.nlm.nih.gov/pubmed/21887379 http://dx.doi.org/10.1371/journal.pone.0024149 |
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