Laforin, a Dual Specificity Phosphatase Involved in Lafora Disease, Is Present Mainly as Monomeric Form with Full Phosphatase Activity

Lafora Disease (LD) is a fatal neurodegenerative epileptic disorder that presents as a neurological deterioration with the accumulation of insoluble, intracellular, hyperphosphorylated carbohydrates called Lafora bodies (LBs). LD is caused by mutations in either the gene encoding laforin or malin. L...

Descripción completa

Detalles Bibliográficos
Autores principales: Dukhande, Vikas V., Rogers, Devin M., Romá-Mateo, Carlos, Donderis, Jordi, Marina, Alberto, Taylor, Adam O., Sanz, Pascual, Gentry, Matthew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162602/
https://www.ncbi.nlm.nih.gov/pubmed/21887368
http://dx.doi.org/10.1371/journal.pone.0024040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162602/
https://www.ncbi.nlm.nih.gov/pubmed/21887368
http://dx.doi.org/10.1371/journal.pone.0024040

Ejemplares similares