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Regulation of miR-146a by RelA/NFkB and p53 in STHdh(Q111)/Hdh(Q111) Cells, a Cell Model of Huntington's Disease
Huntington's disease (HD) is caused by the expansion of N-terminal polymorphic poly Q stretch of the protein huntingtin (HTT). Deregulated microRNAs and loss of function of transcription factors recruited to mutant HTT aggregates could cause characteristic transcriptional deregulation associate...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162608/ https://www.ncbi.nlm.nih.gov/pubmed/21887328 http://dx.doi.org/10.1371/journal.pone.0023837 |