Aberrant expression of the polarity complex atypical PKC and non-muscle myosin IIA in active and inactive inflammatory bowel disease

Epithelial barrier function is contingent on appropriate polarization of key protein components. Work in intestinal epithelial cell cultures and animal models of bowel inflammation suggested that atypical PKC (aPKC), the kinase component of the Par3–Par6 polarity complex, is downregulated by pro-inf...

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Detalles Bibliográficos
Autores principales: Wald, Flavia A., Forteza, Radia, Diwadkar-Watkins, Runa, Mashukova, Anastasia, Duncan, Robert, Abreu, Maria T., Salas, Pedro J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162632/
https://www.ncbi.nlm.nih.gov/pubmed/21667320
http://dx.doi.org/10.1007/s00428-011-1102-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162632/
https://www.ncbi.nlm.nih.gov/pubmed/21667320
http://dx.doi.org/10.1007/s00428-011-1102-1

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