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An alternative therapy for idiopathic pulmonary fibrosis by doxycycline through matrix metalloproteinase inhibition

BACKGROUND: Idiopatiic pulmonary fibrosis (IPF) is a disease of dysregulated fibrogenesis with abnormal matrix metalloproteinase (MMPs) activity, angiogenesis, and profibrotic milieu wherein MMPs inhibition appears to be target-based therapy. We evaluated the role of doxycycline as a nonspecific inh...

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Detalles Bibliográficos
Autores principales: Mishra, Amartya, Bhattacharya, Parthasarathi, Paul, Sumit, Paul, Rantu, Swarnakar, Snehasikta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162753/
https://www.ncbi.nlm.nih.gov/pubmed/21886950
http://dx.doi.org/10.4103/0970-2113.83972