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An alternative therapy for idiopathic pulmonary fibrosis by doxycycline through matrix metalloproteinase inhibition
BACKGROUND: Idiopatiic pulmonary fibrosis (IPF) is a disease of dysregulated fibrogenesis with abnormal matrix metalloproteinase (MMPs) activity, angiogenesis, and profibrotic milieu wherein MMPs inhibition appears to be target-based therapy. We evaluated the role of doxycycline as a nonspecific inh...
Autores principales: | Mishra, Amartya, Bhattacharya, Parthasarathi, Paul, Sumit, Paul, Rantu, Swarnakar, Snehasikta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162753/ https://www.ncbi.nlm.nih.gov/pubmed/21886950 http://dx.doi.org/10.4103/0970-2113.83972 |
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