Poly(I:C) promotes TNFα/TNFR1-dependent oligodendrocyte death in mixed glial cultures

BACKGROUND: Activation of glial cells via toll-like receptors (TLRs) and other intracellular pathogen recognition receptors promotes the release of potentially toxic acute phase reactants such as TNFα and nitric oxide into the extracellular space. As such, prolonged glial activation, as is thought t...

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Detalles Bibliográficos
Autores principales: Steelman, Andrew J, Li, Jianrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162898/
https://www.ncbi.nlm.nih.gov/pubmed/21812954
http://dx.doi.org/10.1186/1742-2094-8-89

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162898/
https://www.ncbi.nlm.nih.gov/pubmed/21812954
http://dx.doi.org/10.1186/1742-2094-8-89

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