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Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib

BACKGROUND: Several proteins that promote angiogenesis are overexpressed in hepatocellular carcinoma (HCC) and have been implicated in disease pathogenesis. Sunitinib has antiangiogenic activity and is an oral multitargeted inhibitor of vascular endothelial growth factor receptors (VEGFRs)-1, -2, an...

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Detalles Bibliográficos
Autores principales: Harmon, Charles S, DePrimo, Samuel E, Raymond, Eric, Cheng, Ann-Lii, Boucher, Eveline, Douillard, Jean-Yves, Lim, Ho Y, Kim, Jun S, Lechuga, Maria José, Lanzalone, Silvana, Lin, Xun, Faivre, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162912/
https://www.ncbi.nlm.nih.gov/pubmed/21787417
http://dx.doi.org/10.1186/1479-5876-9-120