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Molecular evolution of the LNX gene family

BACKGROUND: LNX (Ligand of Numb Protein-X) proteins typically contain an amino-terminal RING domain adjacent to either two or four PDZ domains - a domain architecture that is unique to the LNX family. LNX proteins function as E3 ubiquitin ligases and their domain organisation suggests that their ubi...

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Detalles Bibliográficos
Autores principales: Flynn, Michael, Saha, Orthis, Young, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162930/
https://www.ncbi.nlm.nih.gov/pubmed/21827680
http://dx.doi.org/10.1186/1471-2148-11-235