ss-TEA: Entropy based identification of receptor specific ligand binding residues from a multiple sequence alignment of class A GPCRs

BACKGROUND: G-protein coupled receptors (GPCRs) are involved in many different physiological processes and their function can be modulated by small molecules which bind in the transmembrane (TM) domain. Because of their structural and sequence conservation, the TM domains are often used in bioinform...

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Detalles Bibliográficos
Autores principales: Sanders, Marijn PA, Fleuren, Wilco WM, Verhoeven, Stefan, van den Beld, Sven, Alkema, Wynand, de Vlieg, Jacob, Klomp, Jan PG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162937/
https://www.ncbi.nlm.nih.gov/pubmed/21831265
http://dx.doi.org/10.1186/1471-2105-12-332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162937/
https://www.ncbi.nlm.nih.gov/pubmed/21831265
http://dx.doi.org/10.1186/1471-2105-12-332

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