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ss-TEA: Entropy based identification of receptor specific ligand binding residues from a multiple sequence alignment of class A GPCRs
BACKGROUND: G-protein coupled receptors (GPCRs) are involved in many different physiological processes and their function can be modulated by small molecules which bind in the transmembrane (TM) domain. Because of their structural and sequence conservation, the TM domains are often used in bioinform...
Autores principales: | Sanders, Marijn PA, Fleuren, Wilco WM, Verhoeven, Stefan, van den Beld, Sven, Alkema, Wynand, de Vlieg, Jacob, Klomp, Jan PG |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162937/ https://www.ncbi.nlm.nih.gov/pubmed/21831265 http://dx.doi.org/10.1186/1471-2105-12-332 |
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