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Transition of tumor-associated macrophages from MHC class II(hi )to MHC class II(low )mediates tumor progression in mice
BACKGROUND: Tumor-associated macrophages (TAMs) are the most abundant immune cells within the tumor stroma and play a crucial role in tumor development. Although clinical investigations indicate that high levels of macrophage (MΦ) infiltration into tumors are associated with a poor prognosis, the ex...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162940/ https://www.ncbi.nlm.nih.gov/pubmed/21813021 http://dx.doi.org/10.1186/1471-2172-12-43 |