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Transition of tumor-associated macrophages from MHC class II(hi )to MHC class II(low )mediates tumor progression in mice

BACKGROUND: Tumor-associated macrophages (TAMs) are the most abundant immune cells within the tumor stroma and play a crucial role in tumor development. Although clinical investigations indicate that high levels of macrophage (MΦ) infiltration into tumors are associated with a poor prognosis, the ex...

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Detalles Bibliográficos
Autores principales: Wang, Benfan, Li, Qinyan, Qin, Li, Zhao, Siting, Wang, Jinyan, Chen, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162940/
https://www.ncbi.nlm.nih.gov/pubmed/21813021
http://dx.doi.org/10.1186/1471-2172-12-43