Cargando…
A Simple Bias Correction in Linear Regression for Quantitative Trait Association Under Two-Tail Extreme Selection
Selective genotyping can increase power in quantitative trait association. One example of selective genotyping is two-tail extreme selection, but simple linear regression analysis gives a biased genetic effect estimate. Here, we present a simple correction for the bias.
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162965/ https://www.ncbi.nlm.nih.gov/pubmed/21626281 http://dx.doi.org/10.1007/s10519-011-9475-0 |