The Potential Utility of Curcumin in the Treatment of HER-2-Overexpressed Breast Cancer: An In Vitro and In Vivo Comparison Study with Herceptin

HER-2 is an important oncoprotein overexpressed in about 15–25% of breast cancers. We hypothesized that the ability of curcumin to downregulate HER-2 oncoprotein and inhibit the signal transduction pathway of PI3K/Akt, MAPK, and NF-κB activation may be important in the treatment of HER-2-overexpress...

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Detalles Bibliográficos
Autores principales: Lai, Hung-Wen, Chien, Su-Yu, Kuo, Shou-Jen, Tseng, Ling-Ming, Lin, Hui-Yi, Chi, Chin-Wen, Chen, Dar-Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162976/
https://www.ncbi.nlm.nih.gov/pubmed/21876713
http://dx.doi.org/10.1155/2012/486568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162976/
https://www.ncbi.nlm.nih.gov/pubmed/21876713
http://dx.doi.org/10.1155/2012/486568

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