Type I interferon signaling limits reoviral tropism within the brain and prevents lethal systemic infection

In vivo and ex vivo models of reoviral encephalitis were utilized to delineate the contribution of type I interferon (IFN) to the host’s defense against local central nervous system (CNS) viral infection and systemic viral spread. Following intracranial (i.c.) inoculation with either serotype 3 (T3)...

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Detalles Bibliográficos
Autores principales: Dionne, Kalen R., Galvin, John M., Schittone, Stephanie A., Clarke, Penny, Tyler, Kenneth L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163031/
https://www.ncbi.nlm.nih.gov/pubmed/21671121
http://dx.doi.org/10.1007/s13365-011-0038-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163031/
https://www.ncbi.nlm.nih.gov/pubmed/21671121
http://dx.doi.org/10.1007/s13365-011-0038-1

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