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Type I interferon signaling limits reoviral tropism within the brain and prevents lethal systemic infection
In vivo and ex vivo models of reoviral encephalitis were utilized to delineate the contribution of type I interferon (IFN) to the host’s defense against local central nervous system (CNS) viral infection and systemic viral spread. Following intracranial (i.c.) inoculation with either serotype 3 (T3)...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163031/ https://www.ncbi.nlm.nih.gov/pubmed/21671121 http://dx.doi.org/10.1007/s13365-011-0038-1 |