The Ethanol Extract of Fructus trichosanthis Promotes Fetal Hemoglobin Production via p38 MAPK Activation and ERK Inactivation in K562 Cells

Pharmacological stimulation of fetal hemoglobin (HbF) expression may be a promising approach for the treatment of beta-thalassemia. In this study, the effects of Fructus trichosanthis (FT) were investigated in human erythroleukemic K562 cells for their gamma-globin mRNA and HbF-induction activities....

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Detalles Bibliográficos
Autores principales: Li, Hui, Ko, Chun Hay, Tsang, Suk Ying, Leung, Ping Chung, Fung, Ming Chui, Fung, Kwok Pui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163070/
https://www.ncbi.nlm.nih.gov/pubmed/21876711
http://dx.doi.org/10.1093/ecam/neq022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163070/
https://www.ncbi.nlm.nih.gov/pubmed/21876711
http://dx.doi.org/10.1093/ecam/neq022

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