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Shortening and Improving the Embryonic Stem Cell Test through the Use of Gene Biomarkers of Differentiation

The embryonic Stem cell Test (EST) is a validated assay for testing embryotoxicity in vitro. The total duration of this protocol is 10 days, and its main end-point is based on histological determinations. It is suggested that improvements on EST must be focused toward molecular end-points and, if po...

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Detalles Bibliográficos
Autores principales: Romero, Andrea C., Vilanova, Eugenio, Sogorb, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163134/
https://www.ncbi.nlm.nih.gov/pubmed/21876691
http://dx.doi.org/10.1155/2011/286034