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Shortening and Improving the Embryonic Stem Cell Test through the Use of Gene Biomarkers of Differentiation
The embryonic Stem cell Test (EST) is a validated assay for testing embryotoxicity in vitro. The total duration of this protocol is 10 days, and its main end-point is based on histological determinations. It is suggested that improvements on EST must be focused toward molecular end-points and, if po...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163134/ https://www.ncbi.nlm.nih.gov/pubmed/21876691 http://dx.doi.org/10.1155/2011/286034 |