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Synergistic Effects between Phosphorylation of Phospholamban and Troponin I Promote Relaxation at Higher Heart Rate

We hypothesized that the extent of frequency-dependent acceleration of relaxation (FDAR) would be less than that of isoproterenol-(ISO-)dependent acceleration of relaxation (IDAR) at the same increment of heart rates, and ISO may improve FDAR. Cardiac function and phosphorylation of PLB and cTnI wer...

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Detalles Bibliográficos
Autores principales: Zhang, Lin, Yu, Yuan, Song, Zhen, Wang, Yun-Ying, Yu, Zhi-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163139/
https://www.ncbi.nlm.nih.gov/pubmed/21876643
http://dx.doi.org/10.1155/2011/651627