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Rapid optimization of gene dosage in E. coli using DIAL strains
BACKGROUND: Engineers frequently vary design parameters to optimize the behaviour of a system. However, synthetic biologists lack the tools to rapidly explore a critical design parameter, gene expression level, and have no means of systematically varying the dosage of an entire genetic circuit. As a...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163176/ https://www.ncbi.nlm.nih.gov/pubmed/21787416 http://dx.doi.org/10.1186/1754-1611-5-10 |