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Molecular characterization of cathepsin B from Clonorchis sinensis excretory/secretory products and assessment of its potential for serodiagnosis of clonorchiasis

BACKGROUND: Cathepsin cysteine proteases play multiple roles in the life cycle of parasites such as food uptake, immune invasion and pathogenesis, making them valuable targets for diagnostic assays, vaccines and drugs. The purpose of this study was to identify a cathepsin B of Clonorchis sinensis (C...

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Detalles Bibliográficos
Autores principales: Chen, Wenjun, Wang, Xiaoyun, Li, Xuerong, Lv, Xiaoli, Zhou, Chenhui, Deng, Chuanhuan, Lei, Huali, Men, Jingtao, Fan, Yongxiu, Liang, Chi, Yu, Xinbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163202/
https://www.ncbi.nlm.nih.gov/pubmed/21794140
http://dx.doi.org/10.1186/1756-3305-4-149