Electroporation increases antitumoral efficacy of the bcl-2 antisense G3139 and chemotherapy in a human melanoma xenograft

BACKGROUND: Nucleic acids designed to modulate the expression of target proteins remain a promising therapeutic strategy in several diseases, including cancer. However, clinical success is limited by the lack of efficient intracellular delivery. In this study we evaluated whether electroporation cou...

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Detalles Bibliográficos
Autores principales: Spugnini, Enrico P, Biroccio, Annamaria, De Mori, Roberta, Scarsella, Marco, D'Angelo, Carmen, Baldi, Alfonso, Leonetti, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163203/
https://www.ncbi.nlm.nih.gov/pubmed/21798045
http://dx.doi.org/10.1186/1479-5876-9-125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163203/
https://www.ncbi.nlm.nih.gov/pubmed/21798045
http://dx.doi.org/10.1186/1479-5876-9-125

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