Ets-1 mediates upregulation of Mcl-1 downstream of XBP-1 in human melanoma cells upon ER stress

Past studies have shown that upregulation of the anti-apoptotic Bcl-2 family protein Mcl-1 is a major adaptive mechanism of melanoma cells to endoplasmic reticulum (ER) stress, and has an important role in resistance of the cells to apoptosis. In this study, we show that the increase in transcriptio...

Descripción completa

Detalles Bibliográficos
Autores principales: Dong, L, Jiang, C C, Thorne, R F, Croft, A, Yang, F, Liu, H, de Bock, C E, Hersey, P, Zhang, X D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163261/
https://www.ncbi.nlm.nih.gov/pubmed/21423203
http://dx.doi.org/10.1038/onc.2011.87

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163261/
https://www.ncbi.nlm.nih.gov/pubmed/21423203
http://dx.doi.org/10.1038/onc.2011.87

Ejemplares similares