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Defective interfering influenza virus confers only short-lived protection against influenza virus disease: Evidence for a role for adaptive immunity in DI virus-mediated protection in vivo

We have shown earlier that a single dose of cloned defective interfering (DI) influenza A virus strongly protects mice from disease following a lethal challenge with different subtypes of influenza A virus. These animals suffered no clinical disease but experienced a subclinical infection which rend...

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Detalles Bibliográficos
Autores principales: Scott, Paul D., Meng, Bo, Marriott, Anthony C., Easton, Andrew J., Dimmock, Nigel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163266/
https://www.ncbi.nlm.nih.gov/pubmed/21762748
http://dx.doi.org/10.1016/j.vaccine.2011.06.114