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Detection, Isolation and Characterization of Principal Synthetic Route Indicative Impurities in Verapamil Hydrochloride

Two unknown impurities were detected in verapamil hydrochloride bulk drug using isocratic reversed-phase high performance liquid chromatography (HPLC). These impurities were isolated by preparative HPLC. Spectral data for the isolated impurities were collected. Based on the spectral data derived fro...

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Detalles Bibliográficos
Autores principales: Srinivasan, Viswanathan, Sivaramakrishnan, Hariharan, Karthikeyan, Balakrishnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163365/
https://www.ncbi.nlm.nih.gov/pubmed/21886903
http://dx.doi.org/10.3797/scipharm.1101-19