Synthesis of Diarylpyrazoles Containing a Phenylsulphone or Carbonitrile Moiety and their Chalcones as Possible Anti-Inflammatory Agents

A series of chalcone-based diarylpyrazoles containing a phenylsulphone or carbonitrile moiety was synthesized. Thus, 3-acetylpyrazoles 6a–c and 10a–c were used as useful substrates in facile synthesis of functional pyrazoles 7a–f and 11a–f, respectively. The anti-inflammatory activity and ulcerogeni...

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Detalles Bibliográficos
Autores principales: Nassar, Ekhlass, Abdel-Aziz, Hatem A., Ibrahim, Hany S., Mansour, Ahmed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163377/
https://www.ncbi.nlm.nih.gov/pubmed/21886900
http://dx.doi.org/10.3797/scipharm.1105-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163377/
https://www.ncbi.nlm.nih.gov/pubmed/21886900
http://dx.doi.org/10.3797/scipharm.1105-14

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