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Synthesis, Characterization and Quantification of Simvastatin Metabolites and Impurities

Simvastatin is used in treatment of hypercholesterolemia because it regulates cholesterol synthesis as a result of its β-hydroxy acid acting as an inhibitor of 3-hydroxy-methylglutaryl coenzyme A (HMG-CoA). The present communication deals with synthesis, characterization and development of accurate,...

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Detalles Bibliográficos
Autores principales: Bhatia, Manish S., Jadhav, Swapnil D., Bhatia, Neela M., Choudhari, Prafulla B., Ingale, Kundan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163378/
https://www.ncbi.nlm.nih.gov/pubmed/21886906
http://dx.doi.org/10.3797/scipharm.1105-16