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Selection for Translation Efficiency on Synonymous Polymorphisms in Recent Human Evolution
Synonymous mutations are considered to be “silent” as they do not affect protein sequence. However, different silent codons have different translation efficiency (TE), which raises the question to what extent such mutations are really neutral. We perform the first genome-wide study of natural select...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163469/ https://www.ncbi.nlm.nih.gov/pubmed/21803767 http://dx.doi.org/10.1093/gbe/evr076 |